Friday, September 10, 2010

Weight Loss Can Release the Toxins From Body Tissues

By John Gever, Senior Editor, MedPage Today
Published: September 09, 2010
Reviewed by Zalman S. Agus, MD; Emeritus Professor
University of Pennsylvania School of Medicine and
Dorothy Caputo, MA, RN, BC-ADM, CDE, Nurse Planner Earn CME/CE credit
for reading medical news
Action Points

* Point out that observational, cross-sectional studies cannot determine causality.

* Note also that the study did not examine whether there were deleterious health consequences due to changes in serum levels of organic pollutants that apparently were released from fat cells as a result of weight loss.

Environmental pollutants trapped in fat cells could be released back into circulation when people shed a lot of weight, researchers said.

According to data collected from among 1,099 adult participants age ≥40 in the CDC's National Health and Nutrition Examination Survey (NHANES), serum concentrations of six persistent organic pollutants were significantly correlated with weight change, according to Duk-Hee Lee, MD, PhD, of Kyungpook National University in Daegu, Korea, and colleagues.

Adjusted correlation coefficients for 10-year weight changes ranged from -0.16 to -0.23 for the six pollutants, with slightly smaller coefficients found for one-year weight changes, the researchers reported online in the International Journal of Obesity.