Wednesday, November 10, 2010

from George Claxton

George Claxton is one of the leading authorities on Agent Orange/Dioxin in the country. Although he is not a scientist he can go toe-to-toe with anyone on the subject of Dioxin contamination and its effects.

For many years industry has said that 2,4-D, which was half of Agent Orange, was safe. And that 2,4-D did not contain the most deadly dioxin which is called TCDD. A 1991 study from Russia clearly shows differently. The name of the study is "Determing Tetrachlorodibenzo-n-dioxins and Tetrachlorodibenzofurans iin the herbicide 2,4-D". The authors were N.A. Klyuev, et al. and it was published in "Doklady, Biological Sciences, vol. 316, no 1, p. 21-23, 1991".

The following statement is made in the study:

"The concentrations of the most toxic congeners were: 2,3,7,8-tetrachlorodibenzo-p-dioxin (1746016) 0.10ng/g and 2,3,7,8 tetrachlorodibenzofuran (51207319) plus 1,2,6,9-tetrachlorodibenzofuran (70648189) 1.34ng/g".

The question that is obvious is Can 2,4-D contain TCDD? I think that the answer is yes.


The chemical industry has built 2 task forces with the purpose of keeping 2,4-D on the market. The reason is money and the poison is claimed to be safe. However, a study in 2007 titled "Herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) induced cytogenetic damage in human lymphocytes in vitro in presence of erythrocytes" points in a different direction. 2,4-D was half of Agent Orange and does contain some dioxins.

The study conclusion states the following:

"The results demonstrated that the presence of erythrocytes in the culture system modulated the DNA and cellular damage inflicted by 2,4-D and 2,4-D DMA into human lymphocytes in vitro as well as both 2,4-D and 2,4-D DMA were more potent genotoxic agents in the presence of human red cells"

This study was published in the journal 'Cell Biology International (vol 31, no. 11, p. 1316-1322, 2007). The authors were Sonia Soloneski, et al.
Faithfully submitted, George Claxton

3 comments:

  1. George,
    Can you review the Da Nang Harbor Report at bluewaternavy.org and provide comments? I would very much appreciate your input.
    navy@bluewaternavy.org

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  2. George,
    I served in Nam 70-71 in Quang Tri. 18 months ago after my Agent Orange study registration exam, it was discovered I had a cancer in my upper chest. It was diagnosed as Malignant Thymoma. I have filed a claim, it was denied and now I am awaiting my appeal hearing.

    I was wondering if in your experience you knew if this type of cancer had any relation to the AO dioxin?
    jsaunde2@tampabay.rr.com

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  3. Let's get one thing straight. 2,4-D is not TCDD. Agent Orange contained 2,4-D and TCDD. 2,4-D is genotoxic but TCDD is not. (Dragan & Schrenk, 2000). Furthermore, All of the studies were done with animals with massive doses of these chemicals.

    Reference

    Dragan,Y.P. and Schrenk, D. (2000). Animal studies addressing the carcinogenicity of TCDD (or related compounds) with an emphasis on tumour promotion. Food Additives and Contaminants 17 (4): 289–302.

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