Among the many who serve in the United States Armed Forces
and who are deployed to distant locations around the world, myriad health
threats are encountered. In addition to those associated with the disruption of
their home life and potential for combat, they may face distinctive disease
threats that are specific to the locations to which they are deployed. U.S.
forces have been deployed many times over the years to areas in which malaria
is endemic, including in parts of Afghanistan and Iraq. Department of Defense
(DoD) policy requires that antimalarial drugs be issued and regimens adhered to
for deployments to malaria-endemic areas. Policies directing which should be
used as first and as second-line agents have evolved over time based on new
data regarding adverse events or precautions for specific underlying health
conditions, areas of deployment, and other operational factors.
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